The importance of loop length on the stability of i-motif structures.
نویسندگان
چکیده
Using UV and srCD spectroscopy it is found that loop length within the i-motif structure is important for both thermal and pH stability, but in contrast to previous statements, it is the shorter loops that exhibit the highest stability.
منابع مشابه
Loop nucleotides impact the stability of intrastrand i-motif structures at neutral pH.
The stability of i-motif structures at neutral pH is of interest due to the potential of these structures to impact gene expression. A systematic investigation of loop sequence and length revealed that certain loop nucleobases stabilize i-motif quadruplexes.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 26 شماره
صفحات -
تاریخ انتشار 2015